IL lymphoplasmacytic enteritis pancreatic insufficiency

Congenital Pulmonary Lymphangiectasia, Gastrointestinal lymphangiectasia, Wireless capsule endoscopy, Antiplasmin Therapy, Medium Chain Triglycerides, Octreotide Treatment, cutaneous lymphangiectasia, primary pulmonary lymphangiectasia, skin lymphangiectasia, support group resources, haemorrhagica conjunctivae, incontinentia pigmenti, Hemihypertrophy, Impaired neutrophil function, dilated lymphatics, eye lymphangiectasia, kidney lymphangiectasia, autologous blood therapy, protein-losing gastroenteropathy, double balloon enteroscopy, malabsorption syndromes, Osteomalacia

Moderators: Birdwatcher, jenjay, Cassie, patoco, Senior Moderators

IL lymphoplasmacytic enteritis pancreatic insufficiency

Postby patoco » Sat Dec 15, 2012 11:28 am

Protein-losing enteropathy in a dog with lymphangiectasia, lymphoplasmacytic enteritis and pancreatic exocrine insufficiency.

Sept 2012

Rodríguez-Alarcón CA, Beristaín-Ruiz DM, Pérez-Casio F, Rivera R, Ochoa G, Martín-Orozco U.


a Veterinary Science Department , Veterinary Hospital, Autonomous University of Juarez , Juarez , Mexico.


protein-losing enteropathy, inflammatory bowel disease, lymphangiectasia, pancreatic exocrine insufficiency

This is a report of seven-year-old male Akita mixed dog, with protein-losing enteropathy (PLE). He had a history of chronic vomiting and diarrhea with anorexia/hyporexia. Previously he suffered acute abdomen about eight months prior to this visit. Our dog showed uncommon combination of diseases that could cause PLE since it was affected by inflammatory bowel disease (IBD), intestinal lymphangiectasia (IL), and exocrine pancreatic insufficiency (EPI). The dog had most of the abnormalities found in IL, as well as hypoalbuminemia, hyperglobulinemia, lymphopenia, hypocalcemia, and hypercholesterolemia. During endoscopy exam, we found changes characteristic of IL such as irregular small white spots. We took biopsies from stomach, duodenum, and cecum. These biopsies showed infiltration by lymphocytes and plasmatic cells in the lamina propria also, the duodenal biopsies showed moderate dilation of the lymphatic vessels. The patient had 2.1 µg/mL of TLI, this result was compatible with EPI. We assume that the first pathology in this animal was IBD, which caused chronic pancreatitis (CP) that in turn progressed to EPI. It is also possible that IL was secondary to IBD. We have reported for the first time the correlation of IBD and EPI in dogs. This should change our approach to treating chronic diarrhea in dogs. Therefore, we propose that dogs diagnosed with EPI should also be subjected to endoscopy and intestinal biopsy. Similarly, to rule out secondary EPI, TLI should be measured routinely in dogs with IBD.

User avatar
Site Admin
Posts: 2175
Joined: Thu Jun 08, 2006 9:07 pm

Return to Lymphangiectasia

Who is online

Users browsing this forum: No registered users and 3 guests